@article{ISI:000451089900055,
 abstract = {In spite of the striking difference between twist-stretch coupling of
dsRNA and dsDNA under external force, dsRNA shows similar structural
polymorphism to dsDNA under different pulling protocols. Our atomistic
MD simulations show that overstretching dsRNA along the 3 direction of
the opposite strands (OS3) leads to the emergence of S-RNA whereas
overstretching along the 5 directions of the opposite strands (OS5)
leads to melting of dsRNA at lower forces. Using the dsRNA morphology
from pulling MD simulations, we use a multiscale method involving ab
initio calculations and Kinetic Monte Carlo (KMC) simulations to
estimate the conductance of dsRNA and find that the conformational
changes drastically affect its conductance. The current through dsRNA
chains drastically drops after a critical stretching length and
critically depends on the pulling protocol. The critical stretching
length for the OS3 pulling case is around 65% higher than that of the
OS5 case.},
 author = {Aggarwal, Abhishek and Bag, Saientan and Maiti, Prabal K.},
 doi = {10.1039/c8cp03574a},
 eissn = {1463-9084},
 issn = {1463-9076},
 journal = {PHYSICAL CHEMISTRY CHEMICAL PHYSICS},
 month = {DEC 7},
 number = {45},
 orcid-numbers = {Aggarwal, Abhishek/0000-0002-3342-6484},
 pages = {28920-28928},
 times-cited = {5},
 title = {Remarkable similarity of force induced dsRNA conformational changes to
stretched dsDNA and their detection using electrical measurements},
 unique-id = {ISI:000451089900055},
 volume = {20},
 year = {2018}
}