@article{ISI:000343016000022,
 abstract = {We report DNA assisted self-assembly of polyamidoamine (PAMAM)
dendrimers using all atom Molecular Dynamics (MD) simulations and
present a molecular level picture of a DNA-linked PAMAM dendrimer
nanocluster, which was first experimentally reported by Choi et al.
(Nano Lett., 2004, 4, 391-397). We have used single stranded DNA (ssDNA)
to direct the self-assembly process. To explore the effect of pH on this
mechanism, we have used both the protonated (low pH) and nonprotonated
(high pH) dendrimers. In all cases studied here, we observe that the DNA
strand on one dendrimer unit drives self-assembly as it binds to the
complementary DNA strand present on the other dendrimer unit, leading to
the formation of a DNA-linked dendrimer dimeric complex. However, this
binding process strongly depends on the charge of the dendrimer and
length of the ssDNA. We observe that the complex with a nonprotonated
dendrimer can maintain a DNA length dependent inter-dendrimer distance.
In contrast, for complexes with a protonated dendrimer, the
inter-dendrimer distance is independent of the DNA length. We attribute
this observation to the electrostatic complexation of a negatively
charged DNA strand with the positively charged protonated dendrimer.},
 author = {Mandal, Taraknath and Kumar, Mattaparthi Venkata Satish and Maiti,
Prabal K.},
 doi = {10.1021/jp504175f},
 issn = {1520-6106},
 journal = {JOURNAL OF PHYSICAL CHEMISTRY B},
 month = {OCT 9},
 number = {40},
 orcid-numbers = {Maiti, Prabal/0000-0002-9956-1136
Kumar, M.Venkata Satish/0000-0002-5238-753X},
 pages = {11805-11815},
 researcherid-numbers = {Maiti, Prabal/B-6335-2009
Kumar, M.Venkata Satish/M-1379-2017},
 times-cited = {12},
 title = {DNA Assisted Self-Assembly of PAMAM Dendrimers},
 unique-id = {ISI:000343016000022},
 volume = {118},
 year = {2014}
}